Dr Marc C Kimber

Lecturer in Organic Chemistry
BSc(Hons) Adelaide, PhD Adelaide

Telephone: +44(0)1509 22 2570
E-mail: M.C.Kimber@lboro.ac.uk

Background

PhD University of Adelaide 1998; Postdoctoral Fellow University of Sydney (Prof. Margaret M. Harding, Streptonigrin analogues) 1998-1999; Postdoctoral Fellow University of Adelaide (Prof. Dennis K. Taylor, 1,2-dioxine chemistry) 2000-2001; Postdoctoral Fellow University of Nottingham (Prof. J. Stephen Clark, Gambieric Acid A) 2002-2004; Senior Scientist, Evotec Oxfordshire 2004-2006; Research Fellow University of Nottingham (Prof. Christopher J. Moody, Nosiheptide) 2006-2007; Teaching Fellow in Organic Chemistry University of Nottingham (Nosiheptide) 2007-2008; Lecturer in Organic Chemistry Loughborough University 2008 – present.

Research Interests

Research Interests include total synthesis, catalysis utilising organometallics and the use of chiral cleft molecules for molecular recognition and catalysis.

For a further information visit the MCK group webpage.

Selected Publications

• Synthesis of Ptaeroxylin (Desoxykarenin): An Unusual Chromone from the Sneezewood Tree Ptaeroxylon obliquum. Muscarella, M; Kimber, M. C.; Moody, C. J. Synlett, 2008, 14, 2101.
• Construction of Macrocyclic Thiodepsipeptides: Synthesis of a Nosiheptide ‘Southern Hemisphere’ Model System. Kimber, M. C.; Moody, C, J. Chem.  Comm. 2008, 591.
• Rapid Two-Directional Synthesis of the F-J Fragment of the Gambieric Acids by Iterative Double Ring-Closing Metathesis. Clark, J. S.; Kimber, M. C.; Robertson, J.; McErlean, C. S. P.; Wilson, C. Angew. Chem. Int. Ed., 2005, 44, 6157.
• Construction of Building Blocks for Polyether Synthesis Using Sequential Catalytic Ring-Closing Metathesis and Cross Metathesis. Clark, J. S.; Elustondo, F.; Kimber, M. C. Chem. Comm. 2004, 2470.
• A Novel Synthesis Of Functionalised Tetrahydrofurans by an Oxa-Michael/Michael Cyclisation of γ-Hydroxyenones. Greatrex, B. W.; Kimber, M. C.; Taylor, D. K; Tiekink, E. R. T. J. Org. Chem., 2003, 68(11), 4239.
• 1,2-Dioxines as Masked cis γ-Hydroxy Enones and their Utilisation in the Synthesis of Highly Substituted γ-Lactones. Greatrex, B. W.; Kimber, M. C.; Taylor, D. K; Fallon, G.; Tiekink, E. R. T. J. Org. Chem., 2002, 67(15), 5307.
• An Improved Synthesis of Cyclopropanes Utilizing Stabilized Phosphonates and 1,2-Dioxines. Kimber, M. C.; Taylor. J. Org. Chem., 2002, 67(9), 3142.
• A One-Pot Synthesis of Thiophene and Pyrrole Derivatives from Readily Available 1,2-Dioxines. Hewton, C. E.; Kimber, M. C.; Taylor, D. K. Tet. Letts., 2002, 43, 3199.
• First Examples of the Catalytic Asymmetric Ring-Opening of Meso 1,2-Dioxines Utilising Cobalt(II) Complexes with Optically Active Tetradentate Schiff Base Ligands: Formation of Enantio-enriched Cyclopropanes. Avery, T.; Jenkins, N. F.; Kimber, M. C.; Luptin, D. W.; Taylor, D. K. Chem. Comm., 2002, 28.
• The Reactivity, Synthesis and Application of γ-Hydroxy Enones in Organic Synthesis. Kimber, M. C.; Taylor, D. K. In Trends in Organic Chemistry, 2001, Vol. 9, 53.
• The Synthesis and Fluorescent Properties of Analogues of the Zinc (II) Specific Fluorophore Zinquin Ester.  Kimber. M. C.; Mahadevan, I. B.; Lincoln, S. F.; Ward, A. D.; Tiekink, E. R.T. J. Org. Chem., 2000, 65(24), 8204.
• Synthesis of Functionalised Chiral Carbocyclic Cleft Molecules Complementary to Trögers Base. Kimber, M. C.; Try, A. C.; Painter, L.; Harding, M. M.; Turner, P. J. Org. Chem., 2000, 65(10), 3024.
• The Synthesis of ABC Analogues of the Antitumour Antibiotic Streptonigrin. Kimber, M. C.; Anderberg, P. I.; Harding, M. M. Tetrahedron, 2000, 56(22), 3575.